![]() 2 Infectious viral epidemics causing severe respiratory infections have long been associated with an increased risk of death. In Northern Italy, during the COVID-19 pandemic, out-of-hospital cardiac arrests increased by 58% compared with the same time period in 2019 and were associated with lower rates of sustained return of spontaneous circulation (ROSC). ![]() 1 On April 6, 2020, NYC out-of-hospital cardiac arrests peaked at 305 cases, an increase of almost 10-fold compared with April 6, 2019. On March 1, 2020, the first case of novel coronavirus disease 2019 (COVID-19) was diagnosed in New York City, New York (NYC) by April 25, 2020, 17 118 confirmed and probable deaths due to COVID-19 had already occurred. ![]() These associations remained statistically significant after adjustment for potential confounders (OR for ROSC, 0.59 OR for sustained ROSC, 0.53 ). Compared with 2019, the COVID-19 period had substantial reductions in return of spontaneous circulation (ROSC) (727 of 3989 patients vs 463 of 1336 patients, P < .001) and sustained ROSC (423 of 3989 patients vs 337 of 1336 patients, P < .001), with fatality rates exceeding 90%. Patients with out-of-hospital cardiac arrest during 2020 were older (mean age, 72 vs 68 years), less likely to be white (611 of 2992 vs 382 of 1161 ), and more likely to have hypertension (2134 of 3989 vs 611 of 1336 ), diabetes (1424 of 3989 vs 348 of 1336 ), and physical limitations (2259 of 3989 vs 634 of 1336 ). The incidence of nontraumatic out-of-hospital cardiac arrests in those who underwent EMS resuscitation in 2020 was 3 times the incidence in 2019 (47.5/100 000 vs 15.9/100 000). Most importantly, we thank the prehospital health care workers throughout New York City and this nation for their dedication and sacrifice.Ī total of 5325 patients were included in the main analysis (2935 men mean age, 71 years), 3989 in the COVID-19 period and 1336 in the comparison period. Role of the Funder/Sponsor: The funders provided data management and access but had no role in the design and conduct of the study collection, analysis, and interpretation of the data preparation, review, or approval of the manuscript and decision to submit the manuscript for publication.Īdditional Contributions: Gretchen Van Wye, PhD, MA Mary Huynh, PhD Joseph Kennedy, MPH and Hiu Tai Chan, MS from the New York City Bureau of Vital Statistics assisted with this study. ![]() Statistical analysis: Lancet, Weiden, Zeig-Owens, Hall.Īdministrative, technical, or material support: Lai, Hall, Prezant.Ĭonflict of Interest Disclosures: None reported.įunding/Support: This study was supported by the City of New York and the Fire Department of the City of New York. Drs Lai and Prezant had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.Ĭoncept and design: Lai, Webber, Hall, Prezant.Īcquisition, analysis, or interpretation of data: All authors.ĭrafting of the manuscript: Lai, Weiden, Webber, Zeig-Owens, Prezant.Ĭritical revision of the manuscript for important intellectual content: Lai, Lancet, Webber, Zeig-Owens, Hall, Prezant. Prezant, MD, Office of Medical Affairs, Fire Department of the City of New York, 9 MetroTech Center, Brooklyn, NY 11201 ( Contributions: Drs Lai and Lancet contributed equally to the study.
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